PREDICTIVE RELEVANCE OF DIFFERENT CLINICAL AND LABORATORY FINDINGS FOR HIGHER MORTALITY IN PATIENTS WITH COVID-19 IN A SINGLE CENTER COHORT: NEUTROPHIL/ LYMPHOCYTE RATIO, HIGH CRP, GGT AND CREATININE LEVELS ARE ASSOCIATED WITH HIGH MORTALITY

Objective: Early detection of mortality risk is important in patients diagnosed with coronavirus disease 2019 (COVID-19). Therefore, we aimed to evaluate the predictive value different clinical and laboratory parameters severity COVID-19. Materials Methods: Patients admitted hospital a diagnosis COVID-19 were evaluated retrospectively. The patients’ admission date, discharge intensive care transfer/ death contact history, smoking, symptoms at time admission, vital markers recorded. Results: study included total 347 patients, whom 168 (48.4%) women. mean age was 59.69±16.87 (14-97) years, while 40.9% (n=142) aged over 65 years. Overall, 10.1% (n=35) required transfer an unit 8.4% (n=29) deceased. When oxygen saturation found be lower group that died. (79.51±6.95) compared survivors (88.78±6.11) (p<0.001). Additionally, male gender (p=0.05), advanced (p<0.001), positive PCR result (p=0.036), congestive heart failure (p=0.044), severe involvement on thorax CT (p<0.001), presence least one comorbidity (p=0.003) observed higher rate group. In multivariate analyses, increased values NLR (HR: 1.04, 95% CI: 1.00-1.08), creatinine (OR: 1.37, 1.13-1.66), CRP (=-0.18, OR: 0.98, 0.97-0.99), GGT 1.006, 1.001-1.012), 5.67, 2.24-14.38), 2.38, 0.98-5.75), any 5.23, 2.08-13.13) associated mortality. Conclusions: Several parameters, such as age, gender, comorbidity, NLR, GGT, levels admission can predict patients. These parameters obtained contribute reduction through closer follow-up these